: Guo Jin (Shijiazhuang, Hebei Medical University Eye Hospital in the second 050,000); Su-Fen Li (Shijiazhuang, Hebei Medical University Eye Hospital in the second 050,000); Shi Feng (Shijiazhuang, Hebei Medical University Eye Hospital in the second 050,000); Zhang Bin (Shijiazhuang, Hebei Medical University Eye Hospital in the second 050000)
male patients, 44 years old. As a result of the body blisters, itching 3 months, in May 20, 1996 revenue of dermatology in our hospital. Check skin: the body can be seen skin redness and blister-like cluster, Nigeria's negative sign, the blister wall tension, Po Kui after formation of local erosion face, oral mucosa, conjunctiva and the right eye can see bullosa Department glans and surface erosion, we can see a large number of Serous effusion. Pathological diagnosis: epidermoid under the blister. Clinical diagnosis: benign mucous membrane pemphigoid. Glucocorticoids given antibiotics and systemic treatment. Local lesions Tu Department Sanguisorba carbon oil treatment. On an after-clear as the right eye in patients with eye pain, headache, ophthalmology consultation was requested. Asked history of patients admitted to hospital when his right eye that is red, tears, accompanied by purulent discharge, with its own drop chloramphenicol eye drops and eye ointment erythromycin treatment. Recently, decreased vision, eye pain increase. Check the eyes: his right hand in front sight, 1.0 left eye. A high degree of congestive heart right eye conjunctiva, edema, temporal were scattered in small sheet erosion; diffuse corneal opacity was gray, and the surrounding area for ulcer thin sheet of the Central looming hypopyon about 3mm, while watching unclear. No abnormal left eye. That line right eye secretions culture. Treatment: anterior chamber puncture, trichloroacetic acid ulcer burning plane, gentamicin 0.5ml subconjunctival injection, local drop by 0.3 percent and ofloxacin Solcoseryl eye, the result is not significant. Pseudomonas aeruginosa bacterial culture to grow only moderately sensitive to neomycin. Fungal culture (a). Diagnosis: right eye merger pemphigus Pseudomonas aeruginosa corneal ulcer. Be gentamicin drops and subconjunctival injection, the disease still can not control. In the same year on June 25 inspection: the right eye see a sense of visual light, mixed conjunctival hyperemia, erosion, we can see the surface of a large number of yellow-green purulent discharge, limbal ring can be seen yellow-white infiltration, the temporal and the bottom edge of the cornea Department iris prolapse, As the former disappeared. Surgery patients to refuse treatment with antibiotics, eye drops to drop. 5 days after the review: the right eye with no light perception vision, the central perforation of the cornea, the eye away from the limitations of contents, peripheral cornea was pale solution. Conjunctival secretions lines culture at the growth of Pseudomonas aeruginosa. His right eye immediately line content extraction, pathological diagnosis: right cornea degeneration and necrosis; right eye endophthalmitis. 3 weeks after the installation of artificial eye piece. Skin was discharged to ease the situation. Discussion of benign mucous membrane pemphigoid also known as cicatricial pemphigoid, pemphigus eye, the conjunctiva pemphigus. This rare disease, the cause is unknown, is a chronic skin blisters and easy to violations of the mucous membrane, in particular, conjunctiva, the blister may subside after the left permanent scars. Of the disease found in young and middle-aged and older, 75% of the patients involved conjunctiva. Glucocorticoid treatment is the drug of choice for this disease. This was a middle-aged patients, the incidence of single-lens reflex, for the performance of the disease in the early bullosa conjunctival erosion and face, combined with general characteristics of the skin lesions and pathological changes, with the eye of the clinical features of pemphigus. Conjunctival lesions should be given early subconjunctival injection of glucocorticoid treatment, at the same time local and systemic application of antibiotics to prevent bacterial infection.